SBC introduces Simoa platform
A new era in low-abundance protein detection
- ꁕ Transcriptome Services ꁕ
- ꁕ Single cell sequencing ꁕ
- ꁕ Immunoassay analysis
- ꁕ Validation Services ꁕ
- Health letter analysis service
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- ꁕ Genome Services ꁕ
- ꁕ Molecular diagnostic products ꁕ
- ꁕ Other products ꁕ
In 1971, Swedish scholars Engvail and Perlmann, Dutch scholars Van Weerman and Schurs reported that the development of immune technology into solid-phase immunoassay methods for detecting trace substances in body fluids, namely enzyme-linked immunosorbent assay (ELISA). ELISA has become a cutting-edge subject in the field of analytical chemistry. It is a special reagent analysis method. It is a new type of immunoassay technology developed on the basis of immunoenzymatic techniques.
WESTERN BLOT is a molecular biology technique that separates components by electrophoresis, transfers them from a gel to a solid support, and then uses specific antibodies against specific amino acid sequences as probes to detect the protein of interest.
Immunoblot, also known as Western blot, is a method for detecting a certain protein in a complex sample based on the specific binding of antigen and antibody. This method is a new immunobiochemical technology developed on the basis of gel electrophoresis and solid-phase immunoassay technology. Due to the high resolution of SDS-PAGE and the high specificity and sensitivity of solid-phase immunoassays, immunoblotting has become a routine technique for protein analysis. Immunoblotting is commonly used to identify a protein, and enables qualitative and semi-quantitative analysis of the protein.
Simoa (Single Molecular Array) technology is based on Quanterix Simoa HD-1 digital single-molecule immunoassay analyzer, which can directly detect ultra-high sensitivity of protein, nucleic acid and other biomarkers in serum and plasma. Simoa will greatly promote cancer, especially Early detection, postoperative monitoring and precise medication. Its main application areas include tumors, nerves, infectious diseases, and immune inflammation. Currently, there are about 200 publications that have cited the technology worldwide, including high-scoring journals Nature, Nature Biotechnology, JEM, JAMA Neurology, and so on.
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